Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Muscles of the Pelvic Floor and Perineum01:26

Muscles of the Pelvic Floor and Perineum

5.9K
The muscles of the pelvic floor and perineum are crucial for supporting the pelvic organs, controlling continence, and aiding in sexual function, childbirth, and core stability. They are typically divided into the superficial perineal layer and the deep pelvic floor layer.
Perineal Layer
The perineum is a diamond-shaped area below the pelvic diaphragm, divided into an anterior urogenital triangle that contains the external genitals and a posterior anal triangle housing the anus. The urogenital...
5.9K
Disorders of the Female Reproductive System01:24

Disorders of the Female Reproductive System

4.8K
The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
4.8K
Microbiota of the Urogenital Tract01:28

Microbiota of the Urogenital Tract

41
The human urogenital system, once thought to be sterile in healthy individuals, is now recognized as a complex microbial habitat. Advancements in molecular sequencing techniques have revealed that even in healthy adults, the kidneys and bladder harbor microbial populations similar to those found in the distal urethra, albeit in much lower abundance. These resident microorganisms, while generally innocuous, can become opportunistic pathogens under conditions that alter the urogenital...
41

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Recreation impact on the early establishment of dune-building grasses <i>Elytrigia juncea</i> and <i>Ammophila arenaria</i> on the beach.

Journal of coastal conservation·2025
Same author

Limited sensitivity of permafrost soils to heavy rainfall across Svalbard ecosystems.

The Science of the total environment·2024
Same author

Complications of Synthetic Midurethral Slings: Is There a Relevant Discrepancy Between Observational Data and Clinical Trials?

European urology focus·2023
Same author

Fast, High-Fidelity Addressed Single-Qubit Gates Using Efficient Composite Pulse Sequences.

Physical review letters·2023
Same author

Robust Quantum Memory in a Trapped-Ion Quantum Network Node.

Physical review letters·2023
Same author

Shaping the risk for late-life neurodegenerative disease: A systematic review on prenatal risk factors for Alzheimer's disease-related volumetric brain biomarkers.

Neuroscience and biobehavioral reviews·2023

Related Experiment Video

Updated: Apr 3, 2026

Author Spotlight: Advancing Pelvic Prolapse Treatment with a Non-Mesh Approach using Laparoscopic Pectopexy
03:30

Author Spotlight: Advancing Pelvic Prolapse Treatment with a Non-Mesh Approach using Laparoscopic Pectopexy

Published on: October 25, 2024

2.8K

Local Oestrogen for Pelvic Floor Disorders: A Systematic Review.

M A Weber1, M H Kleijn1, M Langendam2

  • 1Department of Obstetrics and Gynaecology, Academic Medical Center, Amsterdam, the Netherlands.

Plos One
|September 19, 2015
PubMed
Summary

Local estrogen therapy effectively treats vaginal atrophy (VA) and may reduce symptoms of overactive bladder (OAB) and urinary incontinence (UI) in postmenopausal women. Further research is needed for pelvic organ prolapse (POP).

More Related Videos

Laparoscopic Non-Mesh Cerclage Pectopexy for Pelvic Organ Prolapse
03:43

Laparoscopic Non-Mesh Cerclage Pectopexy for Pelvic Organ Prolapse

Published on: September 13, 2022

7.0K
Anogenital Distance and Perineal Measurements of the Pelvic Organ Prolapse POP Quantification System
03:49

Anogenital Distance and Perineal Measurements of the Pelvic Organ Prolapse POP Quantification System

Published on: September 20, 2018

21.5K

Related Experiment Videos

Last Updated: Apr 3, 2026

Author Spotlight: Advancing Pelvic Prolapse Treatment with a Non-Mesh Approach using Laparoscopic Pectopexy
03:30

Author Spotlight: Advancing Pelvic Prolapse Treatment with a Non-Mesh Approach using Laparoscopic Pectopexy

Published on: October 25, 2024

2.8K
Laparoscopic Non-Mesh Cerclage Pectopexy for Pelvic Organ Prolapse
03:43

Laparoscopic Non-Mesh Cerclage Pectopexy for Pelvic Organ Prolapse

Published on: September 13, 2022

7.0K
Anogenital Distance and Perineal Measurements of the Pelvic Organ Prolapse POP Quantification System
03:49

Anogenital Distance and Perineal Measurements of the Pelvic Organ Prolapse POP Quantification System

Published on: September 20, 2018

21.5K

Area of Science:

  • Gynecology
  • Urogynecology
  • Menopause Research

Background:

  • Menopause-related oestrogen decline is linked to pelvic floor disorders.
  • Conditions include vaginal atrophy (VA), urinary incontinence (UI), overactive bladder (OAB), and pelvic organ prolapse (POP).

Purpose of the Study:

  • To systematically review evidence on local oestrogen therapy for treating menopausal pelvic floor disorders.
  • Evaluate efficacy for VA, UI/OAB, and POP.

Main Methods:

  • Systematic search of major databases (MEDLINE, EMBASE, Cochrane, PubMed) up to May 2014.
  • Included randomized controlled trials (RCTs) for VA and UI/OAB, and all studies for POP.
  • Independent data extraction and risk of bias assessment.

Main Results:

  • Topical oestrogens improved subjective and urodynamic outcomes, vaginal maturation, and pH compared to placebo.
  • Low doses showed benefit; application methods did not significantly differ.
  • Evidence for POP treatment is limited, often focusing on associated VA symptoms.

Conclusions:

  • Local oestrogen therapy is effective for vaginal atrophy (VA).
  • It appears beneficial for overactive bladder (OAB) and urinary incontinence (UI) symptoms.
  • More research is required to establish the role of local oestrogens in pelvic organ prolapse (POP) prevention and treatment.