Related Experiment Video
Updated: Apr 3, 2026
09:09
Cryosectioning and Immunostaining Mouse Inner Ear Tissue: From Embryonic to Adult Stages
Published on: April 11, 2025
2.4K
Auditory Impairment in Young Type 1 Diabetics
Yanlian Hou1, Xiaoyan Xiao2, Jianmin Ren3
1Department of Endocrinology, Qilu Hospital of Shandong University, Jinan, China; Affiliated Hospital of Taishan Medical University, Taian, Shandong Province, China.
Archives of Medical Research
|September 20, 2015
Summary
Young type 1 diabetics show hearing impairment, including elevated auditory thresholds and slower nerve conduction. Clinical factors like blood pressure and diabetes duration significantly impact their auditory function.
Area of Science:
- Otoacoustic emissions and auditory brainstem response in audiology.
- Diabetology and metabolic syndrome effects on sensory organs.
Background:
- Auditory impairment is an emerging concern in young individuals with type 1 diabetes.
- Understanding the link between diabetes and hearing loss is crucial for early intervention.
Purpose of the Study:
- To assess auditory function in young type 1 diabetics.
- To investigate correlations between clinical indicators and hearing deficits.
Main Methods:
- Auditory function tests were performed on 50 type 1 diabetics and 50 healthy controls.
- Clinical parameters including cholesterol, blood pressure, and HbA1c were measured.
Main Results:
- Type 1 diabetics exhibited significantly elevated auditory thresholds and prolonged auditory brainstem response latencies compared to controls.
- Hearing impairment correlated with HDL-cholesterol, diabetes duration, blood pressure, GHbA1c, and microalbuminuria.
- Distortion product otoacoustic emissions showed reduced responses in diabetic patients, particularly at higher frequencies.
Conclusions:
- Young type 1 diabetics experience auditory threshold elevation, delayed auditory conduction, and cochlear dysfunction.
- Factors such as HDL-cholesterol, diabetes duration, blood pressure, microalbuminuria, GHbA1c, triglyceride levels, and age are associated with auditory impairment in this population.
More Related Videos
Related Concept Videos
01:22Diabetes Mellitus: Overview and Type I Subtype
6.0K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
6.0K
01:22Diabetes Mellitus: Type 2 and Gestational
5.6K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
5.6K
01:15Diabetes: Symptoms, Diagnosis, and Complications
2.8K
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
2.8K
01:20Pathophysiology of Diabetes
4.4K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
4.4K
01:16Insulin: Dosing Regimen and Adverse Effects
1.2K
Insulin-replacement therapy usually includes both long-acting insulin (basal) and short-acting insulin (to cater to postprandial needs). In a diverse group of type 1 diabetes patients, the average daily insulin dose is typically 0.5-0.7 units/kg body weight. However, obese patients and pubertal adolescents may need more due to insulin resistance.
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
1.2K
01:36Carbohydrate Metabolism
15.0K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
15.0K