Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Visual evoked potential abnormalities in chiasmal lesions.

J Brecelj1, M Denislic, M Skrbec

  • 1University Institute of Clinical Neurophysiology, Ljubljana, Yugoslavia.

Documenta Ophthalmologica. Advances in Ophthalmology
|October 1, 1989
PubMed
Summary

Half-field stimulation of visual evoked potentials (VEPs) is more effective in detecting abnormalities in patients with chiasmal area lesions than full-field stimulation. This method reveals subtle changes not apparent with standard VEP testing.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The spectrum of clinical presentation in haploinsufficiency of A20; a case report of a novel mutation in <i>TNFAIP3</i> gene.

Frontiers in pediatrics·2023
Same author

Electroretinography and optical coherence tomography reveal abnormal post-photoreceptoral activity and altered retinal lamination in patients with enhanced S-cone syndrome.

Documenta ophthalmologica. Advances in ophthalmology·2015
Same author

Genetic risk for co-occurrence of type 1 diabetes and celiac disease is modified by HLA-C and killer immunoglobulin-like receptors.

Tissue antigens·2014
Same author

Disability caused by multiple sclerosis is associated with the number of extra cranial venous stenoses: possible improvement by venous angioplasty. Results of a prospective study.

Phlebology·2012
Same author

Characteristics of gastroesophageal reflux and potential risk of gastric content aspiration in children with cystic fibrosis.

Journal of pediatric gastroenterology and nutrition·2009
Same author

The co effect of prophylaxis and radiosynovectomy on bleeding episodes in haemophilic synovitis.

Haemophilia : the official journal of the World Federation of Hemophilia·2008

Area of Science:

  • Neuroscience
  • Ophthalmology
  • Clinical Electrophysiology

Background:

  • Chiasmal area lesions can cause visual field defects.
  • Visual evoked potentials (VEPs) are used to assess the visual pathway's integrity.
  • Standard VEP testing may not always detect subtle abnormalities caused by chiasmal lesions.

Purpose of the Study:

  • To evaluate the efficacy of half-field stimulation in detecting VEP abnormalities in patients with chiasmal area lesions.
  • To compare the diagnostic yield of half-field versus full-field VEP stimulation in this patient group.
  • To characterize the specific VEP abnormalities associated with chiasmal lesions.

Main Methods:

  • Pattern reversal VEPs were recorded from 38 patients with confirmed chiasmal area lesions.

Related Experiment Videos

  • VEPs were elicited using both full-field and half-field (temporal and nasal) stimulation.
  • Abnormalities were defined as nonrecordable or attenuated P100 (abnormal amplitude ratio) or prolonged P100 latency.
  • Lesion locations, including the sella turcica, were assessed via computer tomography.

    • Main Results:

    • Half-field temporal stimulation (crossed fibers) revealed abnormalities in 80% of patients, higher than full-field stimulation (66%).
    • Nonrecordable P100 was the most frequent abnormality with temporal half-field stimulation (42%).
    • Abnormal amplitude ratio was the most common finding with full-field stimulation (41%).
    • Nasal half-field stimulation (uncrossed fibers) detected abnormalities in 32% of responses.
    • Sella turcica lesions were associated with a high incidence of delayed responses (39%) upon crossed fiber stimulation.

    Conclusions:

    • Half-field stimulation enhances the interpretation of VEPs in patients with chiasmal area lesions.
    • This technique can identify VEP abnormalities missed by conventional full-field stimulation.
    • Half-field stimulation provides a more sensitive method for evaluating visual pathway integrity in the presence of chiasmal pathology.