Related Experiment Video
Updated: Apr 3, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
Substance Use in the Perinatal Period
1Department of Psychiatry, Yale School of Medicine, 40 Temple Street, Suite 6B, New Haven, CT, 06510, USA. ariadna.forray@yale.edu.
Perinatal substance use negatively impacts maternal and fetal health. Effective treatments, including contingency management and novel interventions like progesterone, are crucial for addressing this public health issue.
Area of Science:
- Obstetrics and Gynecology
- Public Health
- Addiction Medicine
Background:
- Perinatal substance use is a significant public health concern with severe maternal and fetal consequences.
- Polysubstance use during pregnancy is prevalent and exacerbates adverse outcomes.
- Tobacco, alcohol, and illicit substances are commonly used during pregnancy.
Purpose of the Study:
- To review recent literature on perinatal use of tobacco, alcohol, cannabis, stimulants, and opioids.
- To examine the effects of these substances on maternal and fetal health.
- To explore current and emerging treatment strategies for perinatal substance use.
Main Methods:
- Systematic literature review of recent research.
- Analysis of epidemiological data on substance use in pregnancy.
- Evaluation of treatment efficacy studies.
Main Results:
- Tobacco is the most frequent substance used, followed by alcohol and illicit drugs.
- Adverse maternal and fetal outcomes are associated with perinatal substance and polysubstance use.
- Behavioral interventions, particularly contingency management, demonstrate the highest efficacy.
- Progesterone shows promise as a novel treatment for postpartum cocaine use.
Conclusions:
- Perinatal substance use requires comprehensive management strategies.
- Contingency management is an effective treatment for perinatal substance use disorders.
- Emerging pharmacological interventions warrant further investigation for improved patient outcomes.
More Related Videos
05:13Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes
Published on: February 28, 2025
15:27Construction of Vapor Chambers Used to Expose Mice to Alcohol During the Equivalent of all Three Trimesters of Human Development
Published on: July 13, 2014
Related Concept Videos
Substance Use Disorders Affecting Sleep
Understanding the concepts of physical dependence,...
Development of the Oral Microbiota
Drug Abuse and Addiction: Pharmacological Phenomena
Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla. Benzonatate operates peripherally within the respiratory tract by...
Physiological Barriers
The blood endothelial barrier is the most porous of these. It allows all small ionized, un-ionized, and lipophilic molecules to pass through the endothelial lining into the interstitial space...
Teratogenicity