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Updated: Apr 3, 2026

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation
Published on: May 31, 2016
Artery calcification, osteoporosis, and plasma adiponectin levels in Chinese elderly
Jun-Kun Zhan1, Yi Wang1, Jie-Yu He1
1Geriatric Department of the Second Xiang-Ya Hospital, Institute of Aging and Geriatrics, Central South University, Changsha, Hunan 410011, PR China.
Objectives:
The purpose of this study is to investigate the plasma adiponectin level and thoracic aortic calcification (TAC) in Chinese elderly.
Background:
The association of serum adiponectin levels and thoracic aortic calcification has not been reported.
Methods:
Total plasma adiponectin level was measured by ELISA. TAC was evaluated by posterior-anterior chest radiographs. Osteoporosis was diagnosed using dual energy X-ray absorptiometry.
Results:
The mean plasma adiponectin level was 6.3 ± 3.7 μg/ml, TAC was detected in 58% of subjects, and comorbidities of TAC and osteoporosis were observed in 33.6% subjects. The percentages of TAC or comorbidities of TAC and osteoporosis were higher in subjects with low adiponectin tertile level than that in patients with intermediate or high adiponectin tertile level. Multivariable logistic regression analysis showed that adiponectin level was negatively associated with TAC prevalence.
Conclusions:
Plasma adiponectin level is associated with TAC and lower plasma adiponectin level may be a useful indicator of artery calcification in the elderly.
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