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Updated: Apr 3, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
Published on: March 14, 2017
[Epileptic seizures and hematemesis in a young patient with sickle cell disease]
J Chevalier1, J Villeneuve1, A-L Lecapitaine1
1Service de médecine interne et de maladies infectieuses, CHI Robert-Ballanger, 1, avenue Robert-Ballanger, 93603 Aulnay-sous-Bois, France.
Introduction:
Sickle cell disease is a multi-faceted disease, which can affect all organs. Here, we report the case of a young woman whose clinical presentation was confusing.
Case Report:
An 18-year-old patient from Martinique in Caribbean area presented to the emergency room with widespread pain, as part of a vaso-occlusive crisis. She reported being followed for SS sickle cell anemia, with a history of vaso-occlusive crises and exchange transfusions in the past. Her hemoglobin rate was 83g/L. She was treated with opioid analgesics. Then, she presented several generalized tonic-clonic seizures and major episodes of hematemesis, which proved to be simulated by the patient, whose hemoglobin electrophoresis result was finally AS.
Conclusion:
This patient had therefore the Münchausen syndrome, mimicking sickle cell anemia, like eight other cases reported in the literature.
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