Related Experiment Video
Updated: Apr 3, 2026
08:15
Metabolomic Analysis of Barley by Gas Chromatography/Mass Spectrometry
Published on: November 8, 2024
1.1K
A fermented barley and soybean formula enhances skin hydration
Sein Lee1, Jong-Eun Kim1, Sujin Suk2
1WCU Biomodulation Major, Department of Agricultural Biotechnology, Seoul National University, Seoul 151-921, Korea ; Advanced Institutes of Convergence Technology, Seoul National University, Seoul 151-921, Korea.
Journal of Clinical Biochemistry and Nutrition
|September 22, 2015
Summary
Consuming a barley and soybean formula (BS) significantly improved skin hydration and reduced stratum corneum thickness. This natural supplement shows potential for enhancing skin health and anti-aging benefits.
Area of Science:
- Dermatology
- Nutritional Science
- Cosmeceuticals
Background:
- Skin hydration is crucial for beauty and anti-aging.
- Barley (Hordeum vulgare) and soybean (Glycine max) offer potential skin health benefits.
- Natural product-based treatments are increasingly sought after.
Purpose of the Study:
- To evaluate the skin hydration effects of a yeast-fermented barley and soybean formula (BS) as a dietary supplement.
- To assess the impact of BS on skin barrier function and stratum corneum thickness.
- To investigate the molecular mechanisms underlying BS's effects on skin health.
Main Methods:
- A randomized, placebo-controlled clinical study involving 65 participants over 8 weeks.
- Participants consumed either a placebo or 3g/day of the BS formula.
- Skin hydration, stratum corneum thickness, and molecular markers (hyaluronan, Hyal2, UVB effects) were analyzed.
Main Results:
- Significant increases in facial skin hydration at 4 and 8 weeks, and forearm hydration at 4 weeks in the BS group.
- Reduced stratum corneum thickness on both face and forearm in the BS group.
- In vitro studies showed BS enhanced hyaluronan production, skin barrier function, and recovered UVB-induced hyaluronan downregulation.
Conclusions:
- The barley and soybean formula (BS) effectively enhances skin hydration and barrier function.
- BS demonstrates potential as a health functional food for improving skin health and anti-aging.
- Further development of BS for cosmetic and therapeutic applications is warranted.
Related Concept Videos
01:27Microbes in the Production of Fermented Foods
233
Lactic acid bacteria (LAB) and molds are instrumental in fermenting plant-based foods to enhance preservation and ensure year-round availability. These microbial processes convert plant carbohydrates into organic acids and other metabolites that inhibit spoilage organisms and contribute to the sensory qualities of the final product.In sauerkraut production, cabbage goes through a microbial succession that starts with cocci such as Leuconostoc mesenteroides. These microbes begin fermentation by...
233
01:25Microbes in Beverage Production
238
Alcoholic beverages such as wine, beer, and spirits are the products of microbial fermentation processes that transform simple sugars into ethanol and a wide array of complex flavor compounds. These transformations rely on the metabolic activities of specific yeasts and bacteria, which are selected and controlled to yield the desired beverage characteristics.Wine Fermentation and MaturationWine production begins with the crushing of grapes to release juice and pulp, forming a must that is...
238
01:29Microbes in Food Production
274
Microbial fermentation is central to food biotechnology, enhancing flavor, texture, preservation, and stability. Fermentative microorganisms metabolize carbohydrates into organic acids, alcohols, and other metabolites that inhibit spoilage organisms and improve digestibility while contributing distinctive sensory qualities.In baking, amylases naturally present in flour hydrolyze starch into monosaccharides such as glucose, which Saccharomyces cerevisiae ferments anaerobically. Through...
274
01:22Bioreactor Controls-III
52
Strain improvement is a foundational strategy in industrial microbiology aimed at maximizing microbial productivity, particularly because natural isolates typically yield commercially valuable products in very low concentrations. Although optimizing the culture medium and environmental conditions can improve yields, these adjustments are inherently limited by the organism’s genetic potential. As a result, the focus shifts toward genetic modifications to enhance biosynthetic capacity. The...
52
01:12Renewal of Skin Epidermal Stem Cells
3.2K
The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular...
3.2K
01:29Fermentation
135.1K
Most eukaryotic organisms require oxygen to survive and function adequately. Such organisms produce large amounts of energy during aerobic respiration by metabolizing glucose and oxygen into carbon dioxide and water. However, most eukaryotes can generate some energy in the absence of oxygen by anaerobic metabolism.
Fermentation is a type of metabolic process that occurs in the absence of oxygen, where organic molecules such as glucose are broken down to produce energy. During this process, the...
Fermentation is a type of metabolic process that occurs in the absence of oxygen, where organic molecules such as glucose are broken down to produce energy. During this process, the...
135.1K