[EXPERIMENTAL VALIDATION OF ND:YAG LASER COAGULATION OF THE BLADDER TISSUE]

Interstitial laser coagulation (ILC) is one of the minimally invasive and minimally traumatic methods for the destruction of small lesions in various organs and tissues. Selection of the optimal operation and exposure mode is critical for the safe use of ILC in clinical practice. The in-vivo study of ILC effects on bladder tissue was carried out in 6 rabbits weighing less than 3 kg. Macroscopic and microscopic analysis of the tissue was done directly after the ILK procedure, on days 3 and 7, 14 and 21 following specimen collection of experimental animals. Safety and efficacy of ND: YAG laser impact on bladder tissues were confirmed by morphological study, which established phasing and extent of changes in the bladder tissues. The results allow us to recommend ILC application for the destruction of small size bladder tumors without impairment of the bladder functions, as well as for the treatment of bottom after transurethral resection of bladder cancer.