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Updated: Apr 3, 2026

A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging
Published on: July 14, 2016
[IS AGE-RELATED MACULAR DEGENERATION A MANIFESTATION OF ALZHEIMER'S DISEASE?]
Abstract:
The review conducts clinical morphological and pathogenetic parallels between Alzheimer's disease and age-related macular degeneration. The common embryology, anatomy and physiology of the brain and eye create the preconditions for the emergence of the friendly processes, including pathological aggregation of β-amyloid and neurodegeneration. Based upon the data the authors justify the need for a thorough ophthalmic status study in the daily practice of an ophthalmologist. According to the authors this is promising for the early diagnosis and monitoring of Alzheimer's disease.
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