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[Quality standard study on Pteris multifida].

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    Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica
    |September 23, 2015
    PubMed
    Summary
    This summary is machine-generated.

    This study establishes a quality control method for Pteris multifida, ensuring its safety and efficacy. The validated method accurately quantifies rhoifolin and other key components, setting new quality standards for this medicinal plant.

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    Area of Science:

    • Pharmacognosy and Phytochemistry: Focus on the chemical profiling and quality assessment of medicinal plants.

    Context:

    • Pteris multifida is a traditional Chinese medicine with various therapeutic applications.
    • Ensuring the quality of herbal medicines is crucial for patient safety and treatment efficacy.
    • Existing quality control methods for Pteris multifida may lack specificity and accuracy.

    Purpose:

    • To develop and validate a comprehensive quality control method for Pteris multifida.
    • To establish quality standards for Pteris multifida based on key chemical markers and physical properties.
    • To ensure the consistent quality and safety of Pteris multifida for medicinal use.

    Summary:

    • Established quality control methods for Pteris multifida, including tests for water content, ash, and extractives.
    • Developed a Thin Layer Chromatography (TLC) method and High-Performance Liquid Chromatography (HPLC) assay for rhoifolin quantification.
    • Validated the methodology, demonstrating good linearity, accuracy, and precision for rhoifolin determination.
    • Determined the content range of rhoifolin and other parameters across 16 batches of Pteris multifida.
    • Proposed quality standard limits for water content, total ash, acid-insoluble ash, ethanol-soluble extractives, and rhoifolin content.

    Impact:

    • The validated quality control method provides a specific and accurate tool for assessing Pteris multifida quality.
    • The established quality standards will help ensure the consistent quality and therapeutic efficacy of Pteris multifida.
    • This research contributes to the standardization of traditional Chinese medicine and promotes its reliable use in healthcare.