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Published on: October 22, 2020
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Do tsetse flies only feed on blood?
Philippe Solano1, Ernest Salou2, Jean-Baptiste Rayaisse3
1IRD, UMR INTERTRYP, F-34398 Montpellier, France.
Summary
Tsetse flies, vectors of sleeping sickness, can digest sugar, challenging their strictly blood-feeding reputation. This discovery may lead to new control strategies for this disease vector.
Area of Science:
- Entomology
- Parasitology
- Vector Biology
Background:
- Tsetse flies (Diptera: Glossinidae) transmit trypanosomes causing human sleeping sickness and animal nagana in Subsaharan Africa.
- These insects have been traditionally considered strictly hematophagous, with disease transmission occurring during blood meals.
Purpose of the Study:
- To investigate the potential for tsetse flies to digest sugar, challenging the established understanding of their feeding behavior.
- To assess the impact of sugar feeding on tsetse fly physiology and determine the prevalence of sugar residues in wild populations.
Main Methods:
- Laboratory experiments exposing hungry tsetse flies (Glossina palpalis gambiensis) to water and sugar solutions.
- Analysis of sugar residues in the midguts of wild-caught tsetse flies.
- Evaluation of the effects of glucose concentration and frequency on female fly longevity and fecundity.
Main Results:
- Laboratory tsetse flies readily consumed water and sugar solutions when blood was unavailable.
- Detectable sugar residues were found in 5-10% of wild tsetse flies, varying by species and sex (more females).
- Sugar residues were more frequent in the dry season; high glucose concentrations negatively impacted female longevity and fecundity.
Conclusions:
- Tsetse flies possess the ability to digest sugar, indicating a broader feeding repertoire than previously known.
- This finding fundamentally alters our understanding of tsetse fly biology and feeding behavior.
- The ability to utilize sugar sources, potentially from plants, opens avenues for novel vector control strategies against neglected tropical diseases.

