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Elective Single Embryo Transfer: an update to UK Best Practice Guidelines
Stephen Harbottle1, Ciara Hughes2, Rachel Cutting3
1a Cambridge IVF, Cambridge University Hospitals NHS Trust, Kefford House , Maris Lane Cambridge , UK.
Human Fertility (Cambridge, England)
|September 23, 2015
Summary
Elective single embryo transfer (eSET) reduces multiple pregnancies and births from assisted reproductive technologies (ARTs). This review updates guidelines to help ART clinics implement effective eSET policies, improving patient safety and reducing costs.
Area of Science:
- Reproductive Medicine
- Obstetrics & Gynecology
Background:
- Multiple pregnancies and births remain a significant concern following assisted reproductive technologies (ARTs).
- The multiple pregnancy rate (MPR) is unacceptably high, posing clinical risks and increasing neonatal care costs.
Purpose of the Study:
- To review current evidence on elective single embryo transfer (eSET).
- To provide an updated guideline for ART clinics on implementing effective eSET policies.
Main Methods:
- Review of randomized controlled trials (RCTs), meta-analyses, and economic analyses.
- Analysis of current evidence supporting eSET implementation.
Main Results:
- Evidence from RCTs, meta-analyses, and economic analyses supports eSET policies.
- Northern Europe, Australia, and Japan show high adoption rates of eSET.
Conclusions:
- eSET is crucial for reducing multiple pregnancies in ART.
- Updated guidelines are needed to assist ART clinics in adopting effective eSET strategies.
