Related Experiment Video
Updated: Apr 3, 2026

Laparoscopic Anatomical Right Hemihepatectomy via the In Situ Anterior Approach
Published on: August 8, 2025
Portal Vein Embolization Before Extended Hepatectomy in a Toddler With Mesenchymal Hamartoma
Sylvain Terraz1, Maxime Ronot2, Romain Breguet3
1Departments of Radiology, Hepato-Pancreato-Biliary Centre, sylvain.terraz@hcuge.ch.
Insights
Portal vein embolization successfully induced liver growth in a 14-month-old child before surgery. This technique, previously unreported in young children, reduced the risk of liver failure after tumor removal.
Area of Science:
- Pediatric Surgery
- Interventional Radiology
- Hepatobiliary Surgery
Background:
- Portal vein embolization (PVE) is a standard procedure to increase liver volume before major liver surgery.
- PVE aims to prevent postoperative liver failure by ensuring adequate liver function.
- PVE has not been documented in infants for liver tumor management.
Observation:
- A 14-month-old infant presented with a large, multifocal mesenchymal hamartoma involving the entire right lobe of the liver.
- The tumor necessitated an extended hepatectomy, requiring significant FLR hypertrophy.
- Percutaneous PVE was performed to induce hypertrophy of the left liver lobe (FLR).
Findings:
- The PVE procedure was technically successful in the infant.
- Significant hypertrophy of the FLR was achieved following PVE.
- The patient underwent successful resection of the liver tumor with an adequate FLR.
- No major postoperative complications related to liver insufficiency were observed.
Implications:
- This case demonstrates the feasibility and safety of PVE in a young child for liver tumor resection.
- PVE can be a valuable tool for managing large pediatric liver tumors requiring extensive resection.
- The findings support the expansion of PVE indications to include very young pediatric patients with significant liver lesions.
Abstract:
Portal vein embolization is widely used to induce hypertrophy of the future liver remnant before extended hepatectomy, decreasing the risk of postoperative liver failure. However, this percutaneous procedure has not been previously reported in a young child. The present report describes the case of a 14-month-old patient with a large multifocal mesenchymal hamartoma of the entire right liver, successfully resected after induction of future liver remnant hypertrophy by portal vein embolization.

