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Updated: Apr 3, 2026

Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
Published on: February 13, 2021
Dynamic and fluid-structure interaction simulations of bioprosthetic heart valves using parametric design with
Ming-Chen Hsu1, David Kamensky2, Fei Xu1
1Department of Mechanical Engineering, Iowa State University, 2025 Black Engineering, Ames, IA 50011, USA.
Abstract:
This paper builds on a recently developed immersogeometric fluid-structure interaction (FSI) methodology for bioprosthetic heart valve (BHV) modeling and simulation. It enhances the proposed framework in the areas of geometry design and constitutive modeling. With these enhancements, BHV FSI simulations may be performed with greater levels of automation, robustness and physical realism. In addition, the paper presents a comparison between FSI analysis and standalone structural dynamics simulation driven by prescribed transvalvular pressure, the latter being a more common modeling choice for this class of problems. The FSI computation achieved better physiological realism in predicting the valve leaflet deformation than its standalone structural dynamics counterpart.

