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Calcinosis Cutis and Calciphylaxis.

D Jiménez-Gallo1, L Ossorio-García1, M Linares-Barrios1

  • 1Unidad de Gestión Clínica de Dermatología Médico-Quirúrgica y Venereología, Hospital Universitario Puerta del Mar, Cádiz, España.

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|September 24, 2015
PubMed
Summary
This summary is machine-generated.

Calcinosis cutis involves calcium salt deposition in skin, with dystrophic CC being most common. Treatment options include surgery or medications like diltiazem and bisphosphonates.

Keywords:
Calcificación cutáneaCalcifilaxisCalcinosis cutisCalciphylaxisCutaneous calcificationSodium thiosulfateTiosulfato sódico

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Area of Science:

  • Dermatology
  • Pathology

Background:

  • Calcinosis cutis (CC) is characterized by calcium salt deposition in the skin.
  • It presents in five types: calciphylaxis, dystrophic, metastatic, idiopathic, and iatrogenic.
  • Dystrophic CC, the most frequent type, often co-occurs with autoimmune diseases.

Purpose of the Study:

  • To review the diagnosis and treatment of skin calcifying disorders.
  • To provide an overview of calcinosis cutis and calciphylaxis.

Main Methods:

  • Literature review of calcifying skin disorders.
  • Analysis of diagnostic criteria and therapeutic interventions.

Main Results:

  • Calcinosis cutis encompasses various forms, with dystrophic CC linked to autoimmune conditions.
  • Calciphylaxis involves vascular calcification, leading to skin necrosis.
  • Treatment modalities include surgical intervention and pharmacotherapy (e.g., diltiazem, bisphosphonates, sodium thiosulfate).

Conclusions:

  • Effective management of calcinosis cutis and calciphylaxis requires accurate diagnosis and tailored treatment strategies.
  • Understanding the different types and their associations is crucial for patient care.