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[Diazepam (valium) in premedication. Experimental findings]
Revue D'Odonto-Stomatologie
|November 1, 1989
Summary
This study found that diazepam (Valium) reduced anxiety and increased pain tolerance in volunteers. These findings suggest diazepam is effective for anxious patients during dental procedures.
Area of Science:
- Pharmacology
- Neuroscience
- Psychophysiology
Context:
- Dental anxiety and pain management are significant clinical challenges.
- Diazepam is a commonly prescribed benzodiazepine for anxiety and sedation.
Purpose:
- To evaluate the anxiolytic and analgesic effects of oral diazepam.
- To assess diazepam's impact on electrodermal activity and pain threshold.
Summary:
- 10 mg of diazepam was administered to 10 volunteers.
- Electrodermal activity and pain thresholds were measured during electrical stimulation.
- Diazepam decreased autonomic and anticipatory activities, indicating anxiolysis.
- Diazepam increased pain threshold, demonstrating analgesic effects.
Impact:
- Provides evidence for diazepam's efficacy in managing dental anxiety and pain.
- Supports the use of diazepam in patients undergoing dental procedures.
- Highlights the utility of electrodermal activity as a psychophysiological measure.