Cardiovascular drug determination in bioanalysis: an update
Related Experiment Video
Updated: Apr 3, 2026

Dynamic Continuous Blood Extraction from Rat Heart via Noninvasive Microdialysis Technique
Published on: September 13, 2022
Oskar González1, Nerea Ferreirós2, María Encarnación Blanco1
1Department of Analytical Chemistry, Faculty of Science & Technology, University of the Basque Country (UPV/EHU), 48080 Bilbao, Basque Country, Spain.
Abstract:
The great impact of cardiovascular diseases in human health has led to the development of a huge number of drugs and therapies to improve the treatment of these diseases. Cardiovascular drug analysis in biological fluids constitutes an important challenge for analytical scientists. There is a clear need for reliable methods to carry out both qualitative and quantitative analysis in a short time of analysis. Different problems such as drug monitoring, analysis of metabolites, study of drugs interactions, drugs residues or degradation products, chiral separation, and screening and confirmation of drugs of abuse in doping control must be solved. New trends in sample preparation, instrumental and column technology advances in LC and innovations in MS are described in this work.
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