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Changes in the Mother-Placenta-Fetus System Under the Effect of α-Tocopherol in Albino Rats with Normal Pregnancy

A S Ivanova1, L P Peretyatko2, O G Sitnikova2

  • 1Ivanovo State Medical Academy, the Ministry of Health of the Russian Federation, Ivanovo, Russia. asivanova@mail.ru.

Bulletin of Experimental Biology and Medicine
|September 24, 2015
PubMed

The effects of α-tocopherol on the function of the mother-placenta-fetus system and structural changes in the placenta in normal pregnancy were studied in albino rats. The results indicated that inhibition of free radical processes by injections of α-tocopherol in normal pregnancy led to disorders in the feto-maternal circulation, which was proven by morphological changes in the placenta. The disorders in the uteroplacental circulation manifested in the development of small-for-date fetuses and erythrocytosis.

Keywords:
morphologymother–placenta–fetus systemα-tocopherol

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