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Updated: Apr 3, 2026

Real-time Electrophysiology: Using Closed-loop Protocols to Probe Neuronal Dynamics and Beyond
Published on: June 24, 2015
Neurodynamics of up and down transitions in a single neuron
1Institute for Cognitive Neurodynamics, East Chine University of Science and Technology, Shanghai, 200237 People's Republic of China.
Abstract:
Recent experimental studies have revealed that up and down transitions exist in membrane potential of neurons. This paper focuses on the neurodynamical research of these transitions in a single neuron since it is the basic to study the transitions in the neural network for further work. The results show there exists two stable levels in the neuron called up and down states. And transitions between these two states are bidirectional or unidirectional with the values of parameters changing. We also study the periodic spontaneous activity of the transitions between up and down states without any inputting stimulus which coheres with the experimental results.
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