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Geotrichum capitatum respiratory tract infection in a patient with polytrauma
Marina Radic1, Ivana Goic Barisic1, Dorjan Kuscevic2
1Department of Clinical Microbiology, University Hospital Centre Split, Split, Croatia University of Split School of Medicine, Split, Croatia.
Abstract:
Geotrichum capitatum is a rare pathogen that causes opportunistic fungal infections in immunocompromised patients, particulary in patients with hematological malignancies. We report the case of a 72-year patient with polytrauma whose outcome was fatal. During his stay in the intensive care unit (ICU), he received a broad-spectrum antimicrobial therapy and underwent different invasive procedures. After becoming febrile on the 7th day of admission, two consecutive bronchoalveolar lavage (BAL) specimens were taken for microbiological analysis. The isolated species came as G. capitatum, that was identified using VITEK 2. Unfortunately, patient died before fungal identification, so the antifungal therapy wasn't administered. This case presentation emphasizes the importance of Geotrichum capitatum as an emerging fungal pathogen, as well as the significance of the predisponing factors that contributed to development of infection.
Insights
Geotrichum capitatum, a rare fungus, caused a fatal opportunistic infection in an immunocompromised patient. This case highlights the importance of recognizing this emerging pathogen in critically ill individuals.
Area of Science:
- Medical Mycology
- Infectious Diseases
- Critical Care Medicine
Background:
- Geotrichum capitatum is an opportunistic fungal pathogen.
- It primarily affects immunocompromised individuals, especially those with hematological malignancies.
- Risk factors include broad-spectrum antimicrobial therapy and invasive procedures.
Observation:
- A 72-year-old polytrauma patient in the ICU developed a fever on day 7.
- Bronchoalveolar lavage (BAL) specimens identified Geotrichum capitatum.
- The patient's outcome was fatal before antifungal therapy could be initiated.
Findings:
- This case underscores Geotrichum capitatum as an emerging fungal pathogen.
- The patient's clinical course was complicated by polytrauma and intensive care unit stay.
- Predisposing factors likely contributed to the development of this rare fungal infection.
Implications:
- Highlights the need for increased awareness of Geotrichum capitatum in critically ill patients.
- Emphasizes the significance of identifying predisposing factors for opportunistic infections.
- Suggests the importance of timely fungal diagnostics in immunocompromised patients facing invasive procedures.
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