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Abstract:
Cephroxadine is an orally active cephalosporin of third generation. The most important characteristics are: 1) bacterial cell wall synthesis inhibition during active multiplication; 2) wide spectrum of action, including Gram+ and Gram- bacteria and also penicillinase and beta-lactamase producers; 3) possibility of oral administration, quick assimilation and daily moderate dosage (500 mg/12 h). This antibiotic was tested on 71 patients to prevent and resolve dental pre-and post-operating infections. In all tested cases Cephroxadine was very effective and resolved well symptoms on second day, generally. Moreover no patient had any collateral effect to justify interruption of therapy.