Related Experiment Video
Updated: Apr 3, 2026

Detection of MicroRNA Expression in the Kidneys of Immunoglobulin A Nephropathic Mice
Published on: July 8, 2020
MicroRNAs in urine are not biomarkers of multiple myeloma
Lenka Sedlaříková1,2, Lenka Bešše3,4, Soňa Novosadová5
1Babak Myeloma Group, Department of Pathological Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic. lena.sedlarikova@gmail.com.
Background:
In this study, we aimed to identify microRNA from urine of multiple myeloma patients that could serve as a biomarker for the disease.
Results:
Analysis of urine samples was performed using Serum/Plasma Focus PCR MicroRNA Panel (Exiqon) and verified using individual TaqMan miRNA assays for qPCR. We found 20 deregulated microRNA (p < 0.05); for further validation, we chose 8 of them. Nevertheless, only differences in expression levels of miR-22-3p remained close to statistical significance.
Conclusions:
Our preliminary results did not confirm urine microRNA as a potential biomarker for multiple myeloma.
Related Concept Videos
Urine Studies I: Urinalysis
Microbiota of the Urogenital Tract
MicroRNAs

