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A Protocol of Manual Tests to Measure Sensation and Pain in Humans
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Quantitative sensory testing in pain management.

Carlos J Roldan1,2,3,4, Salahadin Abdi1

  • 1Department of Pain Medicine, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

Pain Management
|September 25, 2015
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Summary

Quantitative sensory testing (QST) assesses sensory and pain perception using noninvasive methods. While QST has advanced many fields, its reliability is influenced by individual factors and testing conditions.

Keywords:
neuropathypain medicinequantitative sensory testingsmall peripheral nerve fibers

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Area of Science:

  • Neuroscience
  • Pain Research
  • Sensory Physiology

Background:

  • Quantitative sensory testing (QST) is a noninvasive methodology utilized for evaluating sensory and pain perception.
  • Established for three decades, QST has seen extensive application and development across various scientific disciplines.
  • Its precision and noninvasive nature have driven numerous QST-based research trials.

Purpose of the Study:

  • To review the established applications and advancements in Quantitative Sensory Testing (QST).
  • To highlight the principles of QST, which involve analyzing individual responses to external stimuli.
  • To discuss factors influencing the reliability and reproducibility of QST.

Main Methods:

  • QST employs a range of noninvasive techniques to measure sensory perception.
  • Analysis involves assessing an individual's response to controlled external stimuli.
  • The integrity of the peripheral nervous system (PNS) and sensory pathways is evaluated.

Main Results:

  • QST has demonstrated benefits across multiple scientific disciplines.
  • The method reflects the functional status of the sensory pathway.
  • Reliability and reproducibility can be affected by affective and cognitive characteristics of participants and testers.

Conclusions:

  • QST is a valuable tool for assessing sensory and pain perception.
  • The interpretation of QST results must consider individual psychological and cognitive factors.
  • Despite its contributions, the future trajectory of QST research remains dynamic and evolving.