Related Experiment Video
Updated: Apr 3, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
COAST (Coordinating Options for Acute Stroke Therapy): An Advance Directive for Stroke
Ilana Spokoyny1, Lynette Cederquist2, Brian Clay3
1University of California, San Diego, Department of Neurology, 200 West Arbor Drive -- 8465, San Diego, California 92103-8465 USA. ilana.spokoyny@gmail.com.
Background:
Stroke is a worldwide problem with a limited number of approved treatments. Obtaining informed consent for acute stroke therapy is complicated by the breadth of information that must be communicated in a short period of time, the hectic nature of the emergency environment, the possible lack of understanding by the patient and/or family, and the critically time-sensitive nature of treatment for stroke. Complicating matters even further, patients are often unable to consent for themselves, placing the burden on surrogates to infer patients' wishes regarding treatment, and potentially limiting acute treatment by practitioners.
Innovation:
An advance directive for acute stroke therapy was created, entitled COAST (Coordinating Options for Acute Stroke Therapy). This clinical initiative is being piloted at a large comprehensive stroke center, including the development of the advance directive form, integration of the form with electronic medical records, training healthcare providers, and outreach to patients.
Conclusions:
COAST is an advance directive for stroke designed to make stroke care more efficient, optimize patients' autonomy, improve the quality of healthcare, and streamline the ethical management of complex care decisions in acute stroke. The inherent benefit of COAST is in providing patients and their families with more information regarding stroke and its treatment options, allowing them to take a more active role in their care.
Related Concept Videos
Atherosclerosis IV: Nursing Management
Acute Coronary Syndrome IV: Interprofessional Care
Regulation of Stroke Volume
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
Acute Coronary Syndrome V: Nursing Management
Standards of Care II
Aneurysm IV: Nursing Management

