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Hallmarks of pluripotency.

Alejandro De Los Angeles1,2,3, Francesco Ferrari4, Ruibin Xi4,5

  • 1Stem Cell Transplantation Program, Division of Pediatric Hematology Oncology, Children's Hospital Boston, and Dana-Farber Cancer Institute; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA.

Nature
|September 25, 2015
PubMed
Summary

This study defines the developmental potency of stem cells, focusing on pluripotent stem cells that can generate all cell types. It proposes methods to evaluate stem cell identity and provenance using molecular and functional hallmarks.

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