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Polymers are classified as linear or branched on the basis of their chain architecture. The polymer chains in linear polymers have a long chain-like structure with minimal to no branching at all. Even if a polymer features large substituent groups on the monomer, which appear as branches to the skeleton, it is not considered a branched polymer. A branched polymer contains secondary polymer chains that arise from the main polymer chain. The branching occurs when the polymer growth shifts from...
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PubChem Substance and Compound databases.

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PubChem is a public repository for chemical and biological information, offering Substance, Compound, and BioAssay databases. It provides data submission, standardization, search interfaces, and programmatic access for researchers.

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Area of Science:

  • Biochemistry
  • Cheminformatics
  • Bioinformatics

Background:

  • PubChem, launched in 2004 by NIH, is a major public repository for chemical substances and biological activities.
  • It has evolved into a comprehensive resource for the scientific community over 11 years.
  • PubChem comprises three interconnected databases: Substance, Compound, and BioAssay.

Purpose of the Study:

  • To provide an overview of the PubChem Substance and Compound databases.
  • To detail data sources, contents, organization, and submission processes.
  • To describe search functionalities, programmatic access, and related resources like PubChem3D and PubChemRDF.

Main Methods:

  • Overview of data sources and contents within PubChem databases.
  • Description of data organization and submission procedures (PubChem Upload).
  • Explanation of chemical structure standardization and search interfaces (textual and non-textual).

Main Results:

  • PubChem Substance database stores contributor-submitted chemical information.
  • PubChem Compound database contains unique chemical structures.
  • PubChem BioAssay database houses biological activity data from assays.
  • PubChem3D and PubChemRDF offer 3D structures and RDF-formatted data for enhanced sharing and analysis.

Conclusions:

  • PubChem serves as a vital, integrated resource for chemical and biological information.
  • The platform facilitates data sharing, analysis, and integration through various features and formats.
  • PubChem supports the scientific research community with extensive chemical data and accessibility options.