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Ethical aspects of Fecal Microbiota Transplantation (FMT)

V Daloiso1, R Minacori, P Refolo

  • 1Institute of Bioethics, "A. Gemelli" School of Medicine, Catholic University of the Sacred Heart, Rome, Italy. dsacchini@rm.unicatt.it.

European Review for Medical and Pharmacological Sciences
|September 25, 2015
PubMed

Insights

Fecal Microbiota Transplantation (FMT) treats infections caused by microbiota alterations. While safe, ethical considerations require investigation for optimal clinical implementation of this therapy.

Area of Science:

  • Microbiology
  • Gastroenterology
  • Medical Ethics

Background:

  • The human microbiota plays a crucial role in maintaining health.
  • Alterations in microbiota composition can result from various factors including antibiotics, diet, and surgery.
  • These dysbiotic states are linked to numerous infections and diseases.

Purpose of the Study:

  • To explore the ethical issues surrounding Fecal Microbiota Transplantation (FMT).
  • To provide insights for the improved clinical application of FMT.
  • To address the growing use of Bacteriotherapy as a treatment option.

Main Methods:

  • Literature review on FMT and associated ethical concerns.
  • Analysis of current clinical practices and safety data of FMT.
  • Discussion of ethical frameworks relevant to FMT implementation.

Main Results:

  • FMT is a recognized treatment for conditions arising from microbiota dysbiosis.
  • Current evidence suggests FMT is generally safe with minimal adverse effects.
  • Several ethical considerations warrant careful examination for widespread FMT use.

Conclusions:

  • Fecal Microbiota Transplantation (FMT) offers a promising therapeutic avenue for microbiota-related diseases.
  • Addressing the ethical dimensions of FMT is essential for its responsible and effective clinical integration.
  • Further discussion and guidelines are needed to navigate the ethical landscape of Bacteriotherapy.

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