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The Skin Microbiota

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The human skin serves as a complex ecosystem inhabited by a diverse community of microorganisms, including bacteria, fungi, and viruses. This microbiome plays a critical role in maintaining skin health and defending against pathogenic invaders. The composition of microbial communities varies significantly across different regions of the body, influenced primarily by the local levels of moisture and sebum.Regional Variation in Skin MicrobiotaCutibacterium acnes predominantly colonizes sebaceous...

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Related Experiment Video

Updated: Apr 3, 2026

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

The microbiome and dermatological diseases.

Dorota Mańkowska-Wierzbicka¹, Jacek Karczewski¹, Agnieszka Dobrowolska-Zachwieja¹

¹Poznan University of Medical Sciences in Poznan, Poznan, Poland.

Postepy Higieny I Medycyny Doswiadczalnej (Online)

|September 25, 2015

Summary

The skin microbiota, a collection of microbes on human skin, can become imbalanced (dysbiosis) due to various factors. This imbalance is linked to several skin diseases.

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Area of Science:

Microbiology
Dermatology
Human Microbiome Research

Background:

The human skin hosts a complex community of microorganisms known as the skin microbiota.
Microbiota composition is influenced by host genetics, diet, antibiotic use, hygiene, and infections.
Disruptions in the microbiota, termed dysbiosis, can lead to an overgrowth of harmful bacteria or a reduction in beneficial ones.

Purpose of the Study:

To review the current understanding of the skin microbiota.
To explore the potential role of the skin microbiota in the pathogenesis of dermatological diseases.

Main Methods:

Literature review of existing studies on skin microbiota and skin diseases.
Synthesis of information regarding factors influencing microbiota composition and its connection to disease.

Main Results:

Dysbiosis, or microbial imbalance, is associated with various dermatological conditions.
Specific changes in the skin microbiota composition are observed in different skin diseases.

Conclusions:

The skin microbiota plays a significant role in maintaining skin health.
Understanding the skin microbiota offers potential therapeutic targets for dermatological diseases.