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A case of lymphoproliferative disorder of NK-cells: aggressive immunophenotype but indolent behavior
Min Shi1, Natasha M Savage2, Huda Salman3
1Division of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic 200 First Street SW, Rochester, Minnesota, 55905.
Abstract:
Distinguishing chronic lymphoproliferative disorder of NK-cells from aggressive NK-cell leukemia is critical because they have distinct clinical course and management. Immunophenotyping plays a key role in distinguishing these two entities, however, it could not be used as sole criteria and clinical/laboratory findings are equally important.
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