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Updated: Apr 3, 2026

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
Published on: August 12, 2019
A Novel MAPT Mutation Causing Corticobasal Syndrome Led by Progressive Apraxia of Speech
Charles R Marshall1, Rita Guerreiro2, Steffi Thust3
1Dementia Research Centre, Department of Neurodegenerative Disease, London, UK.
Abstract:
The authors describe a case of corticobasal syndrome led by progressive apraxia of speech, associated with a novel mutation in exon 10 of the MAPT gene. Genetic bases for progressive apraxia of speech and corticobasal syndrome are only rarely described, and have not been described in conjunction.
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