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[Sorsby's pseudo-inflammatory macular dystrophy: laser treatment]
T Segato1, S Piermarocchi, E Midena
1Clinique ophtalmologique de l'Université de Padoue, Padova, Italie.
Journal Francais D'Ophtalmologie
|January 1, 1989
Summary
Sorsby fundus dystrophy is an inherited eye disease causing vision loss. Laser treatment may help delay central vision loss in patients with subretinal neovascularization.
Area of Science:
- Ophthalmology
- Medical Genetics
Background:
- Sorsby fundus dystrophy is an autosomal dominant inherited condition.
- Characterized by progressive visual loss, posterior pole hemorrhages, and exudates.
Observation:
- Presents with diffuse drusen-like deposits, retinal pigment epithelium changes, and choriocapillaris atrophy.
- Subretinal neovascularization can lead to macular edema, hemorrhages, exudates, and disciform scarring.
- Peripheral fundus atrophy is observed in advanced stages.
Findings:
- Three sisters presented with fundus lesions consistent with Sorsby fundus dystrophy.
- Two patients with suspected subretinal neovascularization showed positive response to laser treatment.
- Laser treatment appeared to positively influence the disease course.
Implications:
- Laser treatment may delay central vision loss by preventing leakage and secondary damage.
- While generalized retinal and choroidal atrophy may be unavoidable, vision preservation is possible.
- This suggests a potential therapeutic strategy for managing Sorsby fundus dystrophy.