[Retinal pigment epithelial changes related to central serous retinopathy]

Thirty nine patients (7 females, 32 males) with central serous retinopathy (CSR) have been followed up for 1.6-17.0 years (mean 9.6 +/- 4.2). Eleven eyes had laser therapy, 7 during the initial attack, 4 at the time of the recurrent CSR. In the initial fluorescein angiograms pigment epithelial (PE) changes other than the leaking point were observed in 21 eyes (54%). Comparison of the serial photographs taken during the follow-up period using a red filter (600 nm, Wratten No. 25) showed progression of PE changes in 25 eyes (64%). In most eyes PE changes remained, however, mild. More pronounced PE atrophy developed in 10 eyes (26%), and a disciform lesion in 1 eye. The latest visual acuity was 0.5 or better in 35 eyes (90%).