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Autopsy report for chemical burns from cresol solution
Yuko Emoto1, Katsuhiko Yoshizawa2, Nobuaki Shikata3
1Department of Pathology II, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka 573-1010, Japan; Medical Examiner's Office of Hyogo Prefecture, 2-1-31 Arata-machi, Hyogo-ku, Kobe, Hyogo 650-0017, Japan.
Summary
Cresol ingestion causes severe gastrointestinal corrosive injuries and systemic shock. This case highlights the direct irritation and toxic effects of cresol poisoning.
Area of Science:
- Toxicology
- Gastroenterology
- Forensic Pathology
Background:
- Cresol is a disinfectant and insecticide with known corrosive properties.
- Oral cresol exposure can lead to direct chemical burns in the gastrointestinal tract.
Observation:
- A case of suicidal poisoning involving saponated cresol solution ingestion in an octogenarian male.
- The patient was found deceased 14 hours post-exposure to less than 500 mL of cresol solution.
Findings:
- Macroscopic examination revealed corrosive lesions on skin, mouth, oral cavity, esophagus, and stomach.
- Histopathology showed coagulative necrosis and vascular dilatation in the esophagus, stomach, and duodenum.
- Systemic effects included pulmonary edema, cerebral edema, and acute tubular necrosis, indicative of shock.
Implications:
- This case underscores the severe irritant and toxic effects of cresol.
- It provides valuable insight into the direct tissue damage and systemic shock induced by corrosive substance ingestion.
- Highlights the critical need for prompt medical intervention in cases of corrosive poisoning.