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A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3
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Structural Studies of IRF4 Reveal a Flexible Autoinhibitory Region and a Compact Linker Domain

Soumya G Remesh1, Vishaka Santosh1, Carlos R Escalante2

  • 1From the Department of Physiology and Biophysics, Virginia Commonwealth University, School of Medicine, Richmond, Virginia 23298.

The Journal of Biological Chemistry
|September 26, 2015
PubMed

Keywords:
gene regulationinterferon regulatory factor (IRF)small angle x-ray scattering (SAXS)structural biologytranscription factorx-ray crystallography

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