Related Experiment Video
Updated: Apr 3, 2026

Standardized Measurement of Nasal Membrane Transepithelial Potential Difference NPD
Published on: September 13, 2018
Analog front-end measuring biopotential signal with effective offset rejection loop
Seunghyun Lim1, Hyunho Kim1, Haryong Song1
1Department of Electronics, Chungnam National University, Daejeon 305-764, Korea.
Abstract:
This paper presents an analog front-end (AFE) IC design for recording biopotential signals. The AFE employs a capacitively coupled instrumentation amplifier to achieve a low-noise and high-common mode rejection ratio (CMRR) system. A ripple reduction loop is proposed to reduce the ripple generated by the up-modulating chopper. The low frequency noise is attenuated by an input AC coupling capacitor, and is attenuated again by a DC servo loop. The proposed AFE features a differential gain of 71 dB, and a CMRR of 89 dB, at 50 Hz. Furthermore, the proposed AFE can robustly acquire biopotential signals even in the presence of an input offset and ripples.
Related Concept Videos
Instrumentation Amplifier
To overcome this challenge, an ECG machine utilizes an instrumentation amplifier. This specialized amplifier is...
Bode Plots Construction
Op Amp AC Circuits
Second-order Op Amp Circuits
The analysis of such circuits follows a systematic approach, similar to the second-order RLC circuits. In practical scenarios, bulky inductors are rarely employed due to their size and weight. This means...

