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Exudative pericarditis in the evolution of a diffuse large B-cell lymphoma
Cristina Bagacean1, Adrian Tempescul2, Jean-Christophe Ianotto2
1Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Insights
Cardiac involvement in non-Hodgkin's lymphoma is rare but serious. This case highlights PET-CT scan diagnosis of lymphomatous pericarditis alongside lymphoma remission.
Area of Science:
- Cardiology
- Oncology
- Medical Imaging
Background:
- Cardiac involvement in non-Hodgkin's lymphoma (NHL) is uncommon and associated with poor prognosis.
- Clinical presentations vary, with heart failure being the most frequent.
- Diagnosis typically relies on cardiac ultrasound.
Observation:
- A case of lymphomatous pericarditis in an NHL patient is presented.
- The diagnosis was established using a positron emission tomography-computed tomography (PET-CT) scan.
- This occurred concurrently with complete isotopic remission of mediastinal lymph nodes after chemotherapy.
Findings:
- PET-CT scan successfully diagnosed lymphomatous pericarditis.
- The cardiac involvement was identified despite successful chemotherapy leading to lymphoma remission.
- This suggests potential for cardiac involvement even during systemic disease control.
Implications:
- PET-CT may offer a valuable diagnostic tool for cardiac lymphoma.
- Early detection of cardiac involvement is crucial for managing NHL patients.
- Further research is needed to understand the clinical significance and management of cardiac involvement during lymphoma remission.
Abstract:
Cardiac involvement in non-Hodgkin's lymphoma is a rare occurrence with a dismal prognosis, which may evolve with different clinical presentations, the most frequent being heart failure. Diagnosis of cardiac involvement is generally made by cardiac ultrasound. We report a case of lymphomatous pericarditis in the evolution of a non-Hodgkin's lymphoma, diagnosed by PET-CT scan, and occurring concomitantly with complete isotopic remission of enlarged mediastinal lymph nodes following chemotherapy.
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