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Published on: October 20, 2012
Local anesthetic wound infusion versus standard analgesia in paediatric post-operative pain control
M S Machoki1, A J W Millar2, H Albetyn2
1Red Cross War Memorial Children's Hospital, University of Cape Town, Cape Town, Western Cape, South Africa. stanmugambi@yahoo.co.uk.
Insights
Continuous local anesthetic wound infusion (CLAWI) effectively manages pediatric post-operative pain, reducing opiate needs. This safe and reliable technique offers improved recovery, including faster mobilization and feeding.
Area of Science:
- Pediatric Anesthesiology
- Pain Management
- Surgical Recovery
Background:
- Local anesthetic wound infusion shows promise in adults for pain management.
- Pediatric application of local anesthetic wound infusion is less established, with limited prospective trials.
Purpose of the Study:
- To evaluate the efficacy and safety of continuous subfascial local anesthetic wound infusion (CLAWI) for post-operative pain control in children undergoing abdominal surgery.
- To compare CLAWI with epidural bupivacaine (EPI) and standard post-operative analgesia (SAPA) in pediatric patients.
Main Methods:
- A prospective trial comparing subfascial continuous local anesthetic wound infusion (CLAWI) with bupivacaine to epidural bupivacaine (EPI) and standard analgesia (SAPA).
- Patients received either CLAWI, EPI, or SAPA, with pain scores and morphine requirements monitored.
- Secondary outcomes included time to full feeds, urinary catheter duration, and mobilization.
Main Results:
- CLAWI demonstrated lower average pain scores (2.5) compared to EPI (3.0) and SAPA (3.5).
- Patients in the CLAWI group required significantly less morphine and had shorter durations for urinary catheter use and mobilization (2 days vs. 4 days).
- No complications related to the wound or bupivacaine were observed in the CLAWI group.
Conclusions:
- Continuous subfascial bupivacaine infusion is a safe, reliable, and effective method for pediatric post-operative pain management.
- CLAWI significantly reduces opioid requirements and improves key recovery parameters in children.
- This technique offers a valuable alternative for post-operative analgesia in pediatric surgical patients.
Introduction:
Local anesthetic wound infusion has shown promising results in adults. Its use in children is limited to some centers and there are only a few prospective trials in this group of patients.
Methods:
Sub-fascial continuous local anaesthetic wound infusion (CLAWI) (0.2% Bupivacaine) plus intravenous paracetamol and rescue intravenous morphine was compared to: (a) Epidural bupivacaine (EPI) plus paracetamol and rescue intravenous morphine for patients undergoing laparotomy. (b) Intravenous morphine and paracetamol (standard post-operative analgesia-SAPA) in children undergoing Lanz incision laparotomy for complicated appendicitis. 'InfiltralLong', PANJUNK(®) catheters were placed sub-fascially after peritoneal closure for post-operative bupivacaine infusion. Pain scores were recorded regularly by the same blinded pain specialist. The primary outcomes were pain control and total morphine. The secondary outcomes were time to full feeds, mobilization requirement for urinary catheter and complications.
Results:
Sixty patients (18 laparotomy-CLAWI, 17 laparotomy-EPI and 12 appendectomy-CLAWI, and 13 appendectomy-SAPA) were analyzed. The average pain score was 2.5 (1-4) in the CLAWI groups, 3.0 (1-5) in the EPI group and 3.5 (2-5) in the SAPA group. Morphine requirements were markedly less for CLAWI. SAPA and EPI groups required urinary catheters for longer and took longer to mobilize (average 4 days compared to 2 days for CLAWI). There were no wound or bupivacaine complications in the CLAWI group.
Conclusion:
Continuous subfascial bupivacaine infusion is reliable, safe and effective in paediatric post-operative pain control with considerably reduced opiate requirements.
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