Related Experiment Video
Updated: Apr 3, 2026
09:42
Development of a Neonatal Rat Model for Brachial Plexus Birth Injury
Published on: March 27, 2026
134
Central Adaptation following Brachial Plexus Injury
Neil G Simon1, Colin K Franz2, Nalin Gupta3
1St. Vincent's Clinical School, University of New South Wales, Australia.
World Neurosurgery
|September 27, 2015
Summary
Brachial plexus trauma (BPT) recovery involves understanding central and peripheral nervous system adaptations. Harnessing these mechanisms through rehabilitation may improve functional outcomes for young patients.
Area of Science:
- Neuroscience
- Rehabilitation Medicine
- Traumatology
Background:
- Brachial plexus trauma (BPT) frequently impacts young individuals, potentially causing persistent functional impairments.
- Current management relies on monitoring for nerve reinnervation and guiding surgical decisions based on spontaneous recovery.
- Emerging evidence suggests central and peripheral nervous system adaptations are crucial for recovery post-BPT.
Observation:
- BPT necessitates a deeper understanding of the nervous system's adaptive responses.
- Both beneficial (adaptive) and detrimental (maladaptive) changes occur in the central and peripheral nervous systems after BPT.
- These neuroplastic changes significantly influence the patient's functional recovery trajectory.
Findings:
- This review elucidates the adaptive and maladaptive mechanisms at play in the central and peripheral nervous systems following BPT.
- Identified mechanisms directly correlate with functional outcomes, highlighting the complexity of recovery.
- Understanding these neurobiological changes is key to optimizing patient recovery.
Implications:
- Rehabilitation strategies can be tailored to leverage or modulate these intrinsic adaptive mechanisms.
- Interventions aimed at enhancing neuroplasticity may lead to improved functional results after BPT.
- Future research should focus on translating these insights into clinical practice for better patient care.
More Related Videos
Related Concept Videos
01:22Spinal Nerves: Plexus I
3.5K
Nerve plexuses are networks of interlacing nerves that serve as communication hubs to distribute and organize nerve action across various body regions. The nerve plexuses are organized into the cervical plexus located in the neck region, brachial plexus in the shoulder area, lumbar plexus found in the lower back, sacral plexus situated in the pelvis, and coccygeal plexus located in the coccygeal region.
The Cervical Plexus
The cervical plexus, formed by the anterior rami of the first four...
The Cervical Plexus
The cervical plexus, formed by the anterior rami of the first four...
3.5K
01:12Arteries of the Upper Limbs
3.1K
The subclavian artery transitions into the axillary artery as it exits the chest and enters the axillary region. This artery is critical for supplying blood to the shoulder area, including the head of the humerus, through the humeral circumflex arteries. As the vessel continues into the upper arm or brachium, it becomes the brachial artery. This artery plays a key role in vascularizing the brachial region and bifurcates at the elbow into several branches. These branches include the deep...
3.1K
01:21Spinal Nerves: Plexus II
3.2K
The plexuses of the lower body include the lumbar, sacral, and coccygeal plexuses, which innervate the abdomen, pelvis, legs, and coccygeal region. These plexuses control the transmission of sensory information and coordinate motor functions of the lower body.
The Lumbar Plexus
The lumbar plexus is situated within the lumbar region of the back and is primarily formed by the first four lumbar spinal nerves (L1 to L4). This plexus extends its branches into several nerves, including the...
The Lumbar Plexus
The lumbar plexus is situated within the lumbar region of the back and is primarily formed by the first four lumbar spinal nerves (L1 to L4). This plexus extends its branches into several nerves, including the...
3.2K
01:26Flail Chest-II
879
Managing flail chest, a condition characterized by a segment of the chest wall moving independently from the rest of the thoracic cage, requires a comprehensive approach. It includes a thorough assessment of the patient's condition, a diagnostic evaluation to determine the extent of the injury, and the implementation of appropriate medical interventions tailored to the individual's needs.
Assessment:
1. Clinical Evaluation:
History:
Assessment:
1. Clinical Evaluation:
History:
879
01:22Burn Injuries
5.0K
Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
5.0K
01:23Peripheral Artery Disease V: Postoperative Nursing Management
584
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
584