Which can predict left ventricular size and systolic function: cardiothoracic ratio or transverse cardiac diameter
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Published on: February 3, 2014
Yinsu Zhu1, Hai Xu1, Xiaomei Zhu1
1Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Insights
The cardiothoracic ratio (CTR) is linked to left ventricular (LV) function in depressed ejection fraction patients, but transverse cardiac diameter (TCD) shows stronger correlations across all patients.
Area of Science:
- Cardiology
- Radiology
- Cardiac Imaging
Background:
- Left ventricular (LV) size and systolic function are crucial in assessing cardiac health.
- The cardiothoracic ratio (CTR) and transverse cardiac diameter (TCD) are common radiographic measurements.
- Understanding their correlation with LV parameters is vital for diagnosing and managing heart conditions.
Purpose of the Study:
- To investigate the association between CTR, TCD, and LV size and systolic function.
- To compare these associations in patients with preserved versus depressed LV ejection fraction (LVEF).
Main Methods:
- 181 subjects with suspected coronary artery disease underwent chest radiography (CR) and dual-source CT coronary angiography (DSCT-CA).
- TCD and CTR were measured from CR; LV end-diastolic volume (LVEDV), LV end-systolic volume (LVESV), and LVEF were measured from DSCT-CA.
- Associations were analyzed based on LVEF (<55% depressed, ≥55% preserved).
Main Results:
- Both TCD and CTR were higher in the depressed LVEF group.
- Significant correlations were found between TCD, CTR, and LV parameters (LVEDV, LVESV, LVEF) in the depressed LVEF group.
- TCD correlated positively with LVEDV and LVESV in the preserved LVEF group, while CTR did not show significant associations.
Conclusions:
- CTR is not a reliable indicator of LV size and function in patients with preserved LVEF.
- CTR correlates with LV size and LVEF in patients with depressed LVEF.
- TCD demonstrates stronger correlations with LV size and systolic function, even in patients with preserved LVEF.
Purpose:
The aim of this study is to investigate the association between the cardiothoracic ratio (CTR), transverse cardiac diameter (TCD), and left ventricular (LV) size and systolic function in patients with or without preserved LV ejection fraction (LVEF).
Methods:
A total of 181 subjects suspected with coronary artery disease underwent chest radiography (CR) and dual source computed tomography coronary angiography (DSCT-CA). TCD and CTR were derived from CR. The LV size and systolic function parameters, such as LV end-diastolic volume (LVEDV), LV end-systolic volume (LVESV) and LVEF were measured from DSCT-CA. The association between TCD, CTR and LV size and systolic function parameters were analyzed according to LVEF value (< 55%, depressed LVEF group; versus ≥ 55%, preserved LVEF group).
Results:
Both TCD and CTR were higher in the depressed LVEF group compared with the preserved LVEF group. Significant correlations were found between TCD, CTR and LVEDV, LVESV, LVEF in depressed LVEF group. However, there was no significant association detected between CTR and LV size and systolic function parameters in preserved LVEF group. Both the LVEDV and LVESV showed a positive correlation with TCD in preserved LVEF group.
Conclution:
Although CTR was not a reliable indicator of LV size and systolic function in patients with preserved LVEF, it was correlated with LV size and LVEF in depressed LVEF patients. Furthermore, TCD showed stronger correlations with LV size and systolic function even in patients with preserved LVEF.
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