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Noninvasive Determination of Vortex Formation Time Using Transesophageal Echocardiography During Cardiac Surgery
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Computational fluid dynamics analysis and PIV validation of a bionic vortex flow pulsatile LVAD.

Liang Xu, Ming Yang, Lin Ye

    Technology and Health Care : Official Journal of the European Society for Engineering and Medicine
    |September 28, 2015
    PubMed
    Summary

    This study designed a Left Ventricular Assistant Device (LVAD) with an asymmetric channel to mimic the human ventricle. The device successfully generated a persistent vortex flow, improving hemocompatibility.

    Keywords:
    Bionic vortex flowcomputational fluid dynamicsleft ventricular assist deviceparticle image velocimetry

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    Area of Science:

    • Biomedical Engineering
    • Fluid Dynamics
    • Medical Devices

    Background:

    • Hemocompatibility in Left Ventricular Assistant Devices (LVADs) is significantly influenced by internal flow patterns.
    • Optimizing flow dynamics is crucial for enhancing the performance and safety of LVADs.

    Purpose of the Study:

    • To design an LVAD with an asymmetric inflow/outflow channel arrangement (45° intersection angle) to replicate the left ventricle's vascular structure.
    • To achieve an uninterruptible vortex flow state within the LVAD, similar to that in the human left ventricle.

    Main Methods:

    • Computational Fluid Dynamics (CFD) simulations were performed using ANSYS Workbench to model the asymmetric LVAD.
    • Particle Image Velocimetry (PIV) experiments were conducted to experimentally validate the CFD-derived velocity fields.

    Main Results:

    • CFD simulations demonstrated the generation of a shifting vortex flow, redirecting to the aorta and creating a persistent recirculating flow.
    • Both CFD and PIV results confirmed the development of a stable, persistent vortex throughout the pulsatile cycle.
    • Qualitative flow patterns and quantitative velocity data showed good agreement between CFD and PIV, validating the model.

    Conclusions:

    • The study successfully achieved the objective of creating a persistent, quasi-intra-ventricle vortex flow state within the designed LVAD.
    • This vortex flow state is expected to improve hemocompatibility and mimic natural ventricular function.