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Roux-en-Y Gastric Bypass Operation in Rats
Published on: June 11, 2012
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Long-term outcomes after Roux-en-Y gastric bypass: 10- to 13-year data.
Nabeel R Obeid1, Waqas Malick1, Seth J Concors2
1Department of Surgery, New York University School of Medicine, New York, New York.
Summary
Roux-en-Y gastric bypass (RYGB) offers sustained weight loss and co-morbidity improvement long-term. However, nearly all patients experience nutritional deficiencies, and some require revisional surgery.
Area of Science:
- Bariatric Surgery
- Metabolic and Bariatric Surgery
- Surgical Outcomes
Background:
- Roux-en-Y gastric bypass (RYGB) shows promise for sustained weight loss and co-morbidity improvement in short-to-mid-term follow-ups.
- Limited long-term data exists, with some studies being outdated or using different surgical techniques.
Purpose of the Study:
- To evaluate long-term outcomes of RYGB, focusing on weight loss, co-morbidity remission, nutritional status, and complication rates.
- To provide updated insights into the durability and safety of RYGB over a decade post-surgery.
Main Methods:
- A retrospective study involving patients who underwent RYGB at least 10 years prior.
- Data collected via chart review, office visits, and telephone interviews.
- Exclusion criteria included revisional surgery, with outcomes tracked for weight loss, co-morbidities, complications, and nutritional deficiencies.
Main Results:
- Mean excess weight loss (%EWL) was 58.9% at over 10 years post-RYGB.
- Significant co-morbidity remission rates observed: 46% for hypertension and hyperlipidemia, 58% for diabetes mellitus.
- High incidence of long-term complications (19.5%) and nutritional deficiencies (87%), with 9% requiring revisional surgery for weight regain.
Conclusions:
- RYGB demonstrates significant and sustainable weight loss, particularly in non-super-obese individuals.
- Co-morbidities show substantial improvement and remission a decade after RYGB.
- Nutritional deficiencies are nearly universal, highlighting the need for lifelong monitoring.

