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FREQUENCY OF WOUND INFECTION IN NON-PERFORATED APPENDICITIS WITH USE OF SINGLE DOSE PREOPERATIVE ANTIBIOTICS

Kishwar Ali, Humera Latif, Sajjad Ahmad

    Journal of Ayub Medical College, Abbottabad : JAMC
    |September 29, 2015
    PubMed

    Insights

    Single-dose preoperative antibiotics effectively prevent wound infections in non-perforated appendicitis cases. Post-operative antibiotic use is unnecessary, simplifying treatment and reducing patient exposure.

    Area of Science:

    • Surgical Infection Prevention
    • Clinical Antibiotic Efficacy
    • Appendicitis Management

    Background:

    • Antibiotics are standard for preventing surgical site infections in appendicitis.
    • Evidence suggests routine post-operative antibiotics may be unnecessary for non-perforated appendicitis.
    • Prophylactic antibiotics alone might suffice for uncomplicated cases.

    Purpose of the Study:

    • To determine the incidence of wound infection in non-perforated appendicitis.
    • To evaluate the efficacy of a single preoperative antibiotic dose.
    • To assess the necessity of extended post-operative antibiotic use.

    Main Methods:

    • Observational study design.
    • 121 patients with non-perforated appendicitis included.
    • Single-dose preoperative antibiotics administered, followed by wound infection monitoring for 8 days.

    Main Results:

    • A total of 121 patients (56 male, 65 female) were analyzed.
    • The overall wound infection rate was 5.78% (7 patients), with minor infections resolving conservatively.
    • Single-dose preoperative antibiotics demonstrated high efficacy (94.21%) with no significant association with age or gender.

    Conclusions:

    • A single preoperative antibiotic dose is effective in preventing wound infections in non-perforated appendicitis.
    • Extended post-operative antibiotic therapy is not required for these cases.
    • This approach simplifies treatment protocols and potentially reduces antibiotic resistance.
    Abstract

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