Related Experiment Video
Updated: Apr 2, 2026

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
Published on: January 29, 2018
Associations of Protein Intake and Protein Source with Bone Mineral Density and Fracture Risk: A Population-Based
L Langsetmo1, S I Barr, C Berger
1David Goltzman, Royal Victoria Hospital, CaMos, 687 Pine Ave W, Room E1.64, Montreal, QC H3A 1A1, Email: david.goltzman@mcgill.ca, Telephone: 514-843-1632, FAX: 514-843-1651.
Low protein intake, particularly below 15% of total energy intake, is linked to increased fracture risk in adults over 50. Dairy protein intake was associated with higher bone mineral density (BMD).
Area of Science:
- Nutrition Science
- Bone Health
- Gerontology
Background:
- High dietary protein's impact on bone mineral density (BMD) and fracture risk is debated.
- Previous studies show conflicting results, with limited data on protein source effects.
Purpose of the Study:
- To investigate the association between total protein intake and protein from dairy, non-dairy animal, and plant sources with BMD.
- To determine the relationship between protein intake and BMD change, and incident osteoporotic fractures.
Main Methods:
- Prospective cohort study (Canadian Multicentre Osteoporosis Study) with 6510 participants.
- Protein intake assessed as % of total energy intake (TEI) via food frequency questionnaire.
- BMD measured at baseline and Year 5; incident fractures ascertained annually.
Main Results:
- Dairy protein intake positively correlated with total hip BMD in adults 50+ and men 25-49.
- Adults 50+ with protein intake <12% TEI (women) or <11% TEI (men) had higher fracture risk than those with 15% TEI.
- Fracture risk was not significantly associated with protein source or intake above 15% TEI.
Conclusions:
- Low protein intake (<15% TEI) in adults 50+ is associated with increased fracture risk, contrary to high-protein concerns.
- Protein source influences BMD but not fracture risk.
Related Concept Videos
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Role of Vitamins in Maintaining Bone Health
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Essential Minerals for Bone Health
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
Proteins: Dietary Sources and Requirements
The Bone Matrix
Bone Remodeling

