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Pain Prevention Using Head and Neck Cancer as a Model
Erin M McMenamin1, Marcia Grant1
1Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, and City of Hope National Medical Center, Duarte, California.
Journal of the Advanced Practitioner in Oncology
|September 29, 2015
Summary
Newer antiepileptic drugs (AEDs) show promise in preventing cancer-related pain, potentially reducing opioid use and improving patient quality of life. Further research into optimal dosing and scheduling is recommended for broader application.
Area of Science:
- Oncology
- Pain Management
- Pharmacology
Background:
- Cancer pain is a significant issue impacting patient quality of life.
- Current pain management strategies, including opioid use, are often suboptimal due to patient and provider "opiophobia".
Purpose of the Study:
- To explore the potential of newer antiepileptic drugs (AEDs) in preventing cancer-related pain.
- To assess the efficacy and tolerability of AEDs in managing pain perception in cancer patients.
Main Methods:
- Review of recent literature on AEDs and their effects on pain perception.
- Analysis of patient populations, including those with head and neck cancer, experiencing pain.
Main Results:
- Newer AEDs have demonstrated a capacity to decrease pain perception in various patient groups.
- These AEDs exhibit a mild and well-tolerated side-effect profile.
Conclusions:
- AEDs offer a potential strategy for preventing cancer pain, thereby reducing reliance on opioids.
- Future research should focus on optimizing AED dosage and scheduling for diverse cancer populations to inform clinical guidelines.
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