Related Experiment Video

Updated: Apr 2, 2026

Scalable Syntheses of Graphene Oxide and Reduced Graphene Oxide using Cascade Design Oxidation and Highly Basic Reduction Reactions
08:57

Scalable Syntheses of Graphene Oxide and Reduced Graphene Oxide using Cascade Design Oxidation and Highly Basic Reduction Reactions

Published on: July 3, 2025

2.4K

Facile and Effective Functionalization of Graphene Oxide by Boron-Oxygen Covalent or Bingel Cyclopropanation Reaction

Weibo Yan, Yanfei Xu, Yongsheng Chen

    Journal of Nanoscience and Nanotechnology
    |September 29, 2015
    PubMed

    More Related Videos

    Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions08:56

    Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions

    Published on: November 30, 2022

    3.6K
    Versatile CO2 Transformations into Complex Products: A One-pot Two-step Strategy07:36

    Versatile CO2 Transformations into Complex Products: A One-pot Two-step Strategy

    Published on: November 9, 2019

    8.5K

    Related Concept Videos

    Hydroboration-Oxidation of Alkenes03:08

    Hydroboration-Oxidation of Alkenes

    In addition to the oxymercuration–demercuration method, which converts the alkenes to alcohols with Markovnikov orientation, a complementary hydroboration-oxidation method yields the anti-Markovnikov product. The hydroboration reaction, discovered in 1959 by H.C. Brown, involves the addition of a B–H bond of borane to an alkene giving an organoborane intermediate. The oxidation of this intermediate with basic hydrogen peroxide forms an alcohol.
    12.4K
    Alkynes to Aldehydes and Ketones: Hydroboration-Oxidation02:47

    Alkynes to Aldehydes and Ketones: Hydroboration-Oxidation

    Introduction
    One of the convenient methods for the preparation of aldehydes and ketones is via hydration of alkynes. Hydroboration-oxidation of alkynes is an indirect hydration reaction in which an alkyne is treated with borane followed by oxidation with alkaline peroxide to form an enol that rapidly converts into an aldehyde or a ketone. Terminal alkynes form aldehydes, whereas internal alkynes give ketones as the final product.
    21.9K
    Regioselectivity and Stereochemistry of Hydroboration02:36

    Regioselectivity and Stereochemistry of Hydroboration

    A significant aspect of hydroboration–oxidation is the regio- and stereochemical outcome of the reaction.
    Hydroboration proceeds in a concerted fashion with the attack of borane on the π bond, giving a cyclic four-centered transition state. The –BH2 group is bonded to the less substituted carbon and –H to the more substituted carbon. The concerted nature requires the simultaneous addition of –H and –BH2 across the same face of the alkene giving syn stereochemistry.
    9.7K
    Preparation of Alcohols via Addition Reactions02:15

    Preparation of Alcohols via Addition Reactions

    Overview
    The acid-catalyzed addition of water to the double bond of alkenes is a large-scale industrial method used to synthesize low-molecular-weight alcohols. An acidic atmosphere is required to allow the hydrogen in the water molecule to act as an electrophile and attack the double bond in an alkene. The addition of a proton to the double bond creates a carbocation intermediate. The proton preferentially bonds to the less substituted end of the double bond to create a more stable carbocation...
    8.2K
    Reactions of Aldehydes and Ketones: Baeyer–Villiger Oxidation01:22

    Reactions of Aldehydes and Ketones: Baeyer–Villiger Oxidation

    Baeyer–Villiger oxidation converts aldehydes to carboxylic acids and ketones to esters. The reaction uses peroxy acids or peracids and is often catalyzed by acid. The reaction is named after its pioneers, Adolf von Baeyer and Victor Villiger. The reaction is achieved by a wide range of peracids such as m-chloroperoxybenzoic acid (mCPBA), perbenzoic acid (C6H5COOOH), peracetic acid (CH3COOOH), hydrogen peroxide (H2O2), and tert-butyl hydroperoxide (t-BuOOH).
    The carbonyl center is activated by...
    5.3K
    Alcohols from Carbonyl Compounds: Reduction02:23

    Alcohols from Carbonyl Compounds: Reduction

    Reduction is a simple strategy to convert a carbonyl group to a hydroxyl group. The three major pathways to reduce carbonyls to alcohols are catalytic hydrogenation, hydride reduction, and borane reduction.
    Catalytic hydrogenation is similar to the reduction of an alkene or alkyne by adding H2 across the pi bond in the presence of transition metal catalysts like Raney Ni, Pd–C, Pt, or Ru. Aldehydes and ketones can be reduced by this method, often under mild to moderate heat (25–100°C) and...
    13.2K