Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

DNA Topoisomerases02:02

DNA Topoisomerases

37.6K
Topoisomerases are enzymes that relax overwound DNA molecules during various cell processes, including DNA replication and transcription. These enzymes regulate positive and negative DNA supercoiling without changing the nucleotide sequence. DNA overwinding in a clockwise direction results in positively supercoiled DNA, whereas underwinding in a counterclockwise direction produces negatively supercoiled DNA.
Types and Mechanism of action
Topoisomerases are divided into two main types. ...
37.6K
Single-Strand DNA Binding Proteins01:03

Single-Strand DNA Binding Proteins

17.2K
For successful DNA replication, the unwinding of double-stranded DNA must be accompanied by stabilization and protection of the separated single strands of the DNA. This crucial task is performed by single-strand DNA-binding (SSB) proteins. They bind to the DNA in a sequence-independent manner, which means that the nitrogenous bases of the DNA need not be present in a specific order for binding of SSB proteins to it. The binding of SSB proteins straightens single-stranded DNA (ssDNA) and makes...
17.2K
Homologous Recombination02:31

Homologous Recombination

65.6K
The basic reaction of homologous recombination (HR) involves two chromatids that contain DNA sequences sharing a significant stretch of identity. One of these sequences uses a strand from another as a template to synthesize DNA in an enzyme-catalyzed reaction. The final product is a novel amalgamation of the two substrates. To ensure an accurate recombination of sequences, HR is restricted to the S and G2 phases of the cell cycle. At these stages, the DNA has been replicated already and the...
65.6K
Restarting Stalled Replication Forks02:37

Restarting Stalled Replication Forks

6.6K
DNA replication is initiated at sites containing predefined DNA sequences known as origins of replication. DNA is unwound at these sites by the minichromosome maintenance (MCM) helicase and other factors such as Cdc45 and the associated GINS complex.The unwound single strands are protected by replication protein A (RPA) until DNA polymerase starts synthesizing DNA at the 5’ end of the strand in the same direction as the replication fork. To prevent the replication fork from falling apart,...
6.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Bioinspired cross-aligned multilayered nanocellulose films through shear-induced orientation.

Journal of colloid and interface science·2026
Same author

Noise-induced instability of uniform flow in single-file traffic systems.

PNAS nexus·2026
Same author

A fibril-scale visco-hyperelastic model for the mechanics of vocal-fold tissues.

Frontiers in bioengineering and biotechnology·2026
Same author

Multiscale characterisation of cellulose nanofibril networks using three 3D imaging methods.

Journal of microscopy·2025
Same author

Activation entropy of dislocation glide in body-centered cubic metals from atomistic simulations.

Nature communications·2025
Same author

Van der Waals semiconductor InSe plastifies by martensitic transformation.

Science advances·2024
Same journal

Twist-angle-controlled anomalous gating in bilayer graphene/BN heterostructures.

Nature materials·2026
Same journal

Engineered living materials need engineered EU regulation.

Nature materials·2026
Same journal

Multimodal scanning-probe quantum sensing of quantum materials.

Nature materials·2026
Same journal

Publisher Correction: Ultralow-voltage electrochemical organic light-emitting transistors with pinned and wide lateral recombination.

Nature materials·2026
Same journal

High-Chern-number orbital magnetism in twisted rhombohedral graphene.

Nature materials·2026
Same journal

Programming local confinements in crystalline frameworks through reticular chemistry.

Nature materials·2026
See all related articles

Related Experiment Video

Updated: Apr 2, 2026

DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers
08:00

DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers

Published on: October 25, 2017

7.3K

Reversible dilatancy in entangled single-wire materials.

David Rodney1,2, Benjamin Gadot2,3, Oriol Riu Martinez3

  • 1Institut Lumière Matière, Université Lyon 1-CNRS, F-69622 Villeurbanne, France.

Nature Materials
|September 29, 2015
PubMed
Summary
This summary is machine-generated.

Researchers developed a novel architected material from coiled wire that expands significantly in both tension and compression. This unique property, achieved through wire elongation and reversible steric effects, offers potential for advanced smart devices.

More Related Videos

Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers
08:28

Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers

Published on: September 19, 2017

8.8K
Studying DNA Looping by Single-Molecule FRET
11:27

Studying DNA Looping by Single-Molecule FRET

Published on: June 28, 2014

16.0K

Related Experiment Videos

Last Updated: Apr 2, 2026

DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers
08:00

DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers

Published on: October 25, 2017

7.3K
Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers
08:28

Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers

Published on: September 19, 2017

8.8K
Studying DNA Looping by Single-Molecule FRET
11:27

Studying DNA Looping by Single-Molecule FRET

Published on: June 28, 2014

16.0K

Area of Science:

  • Materials Science
  • Mechanical Engineering
  • Physics

Background:

  • Designing structures with tunable dilatancy is crucial for advanced applications like smart filters and actuators.
  • Achieving rapid dilation in both tension and compression requires materials with an unusual Poisson ratio, varying with strain beyond conventional limits.

Purpose of the Study:

  • To investigate a novel architected material capable of significant and reversible dilatancy under both tensile and compressive loads.
  • To understand the underlying mechanisms governing this unusual mechanical behavior.

Main Methods:

  • Mechanical testing of a three-dimensional architected material composed of a self-entangled coiled wire.
  • Discrete element simulations to analyze material behavior and deformation mechanisms.

Main Results:

  • The coiled wire material demonstrated a large and reversible dilatancy in both tension and compression, behaving uniquely between discrete and continuum media.
  • The observed behavior stems from the interplay between wire elongation and reversible steric rearrangements.

Conclusions:

  • A simple coiled wire architected material exhibits extraordinary dilatancy, offering a new paradigm for designing responsive structures.
  • The hysteretically reversible nature of the rearrangements in elastic fibers is key to the material's performance.