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Holoprosencephaly: report of a case
Insights
This case report details a patient with holoprosencephaly and median cleft lip/palate treated with lip plasty. The modified Tennison
Area of Science:
- Craniofacial Surgery
- Pediatric Neurosurgery
- Medical Genetics
Background:
- Holoprosencephaly (HPE) is a congenital disorder caused by incomplete forebrain division.
- Median cleft lip and palate are common facial anomalies associated with HPE.
- Early surgical intervention is crucial for managing associated craniofacial defects.
Observation:
- A 3-month-old infant presented with features suggestive of holoprosencephaly.
- The patient exhibited a median cleft lip and palate.
- The suspected HPE was of a mild subtype, compatible with long-term survival.
Findings:
- Lip plasty using the modified Tennison's method was successfully performed.
- The surgical intervention addressed the esthetic concerns of the parents.
- The patient is currently under ongoing clinical observation.
Implications:
- This case highlights the importance of early diagnosis and surgical management in mild holoprosencephaly.
- Lip repair can significantly improve the quality of life and cosmetic outcomes for affected infants.
- Multidisciplinary care is essential for optimizing outcomes in patients with complex congenital conditions.
Abstract:
This is a case report of a patient suffering from holoprosencephaly associated with median cleft lip and palate who was treated in our clinic. The present patient was introduced to our hospital at the age of three months. We suspected holoprosencephaly on the basis of the peculiar facial structure. Lip plasty was performed because the holoprosencephaly of the patient would be of the least severe type capable of surviving a long time, and because of the parents' concern about the esthetic aspect. The modified Tennison's method was used. The patient is under follow-up observation at our hospital.