Related Experiment Videos
Holoprosencephaly: report of a case
Aichi-Gakuin Dental Science
|January 1, 1989
Summary
This case report details a patient with holoprosencephaly and median cleft lip/palate treated with lip plasty. The modified Tennison
Area of Science:
- Craniofacial Surgery
- Pediatric Neurosurgery
- Medical Genetics
Background:
- Holoprosencephaly (HPE) is a congenital disorder caused by incomplete forebrain division.
- Median cleft lip and palate are common facial anomalies associated with HPE.
- Early surgical intervention is crucial for managing associated craniofacial defects.
Observation:
- A 3-month-old infant presented with features suggestive of holoprosencephaly.
- The patient exhibited a median cleft lip and palate.
- The suspected HPE was of a mild subtype, compatible with long-term survival.
Findings:
- Lip plasty using the modified Tennison's method was successfully performed.
- The surgical intervention addressed the esthetic concerns of the parents.
- The patient is currently under ongoing clinical observation.
Implications:
- This case highlights the importance of early diagnosis and surgical management in mild holoprosencephaly.
- Lip repair can significantly improve the quality of life and cosmetic outcomes for affected infants.
- Multidisciplinary care is essential for optimizing outcomes in patients with complex congenital conditions.