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111In (III) uptake by inflammatory and normal tissues

Y Ohkubo1, K Abe, H Kohno

  • 1Department of Radiopharmacy, Tohoku College of Pharmacy, Sendai, Japan.

Tissue distributions of 111In (III) in the rats bearing granuloma, inflammatory tissue induced by turpentine oil, were compared with those of 67Ga. The results showed that indium-111 resembles 67Ga in the manner of uptake by inflammatory and normal soft tissues. The effect of cold-InCl3 on 111In (III) uptake showed that transferrin is not involved in the uptake of 111In (III) into inflammatory tissues but is involved in the uptake into liver and spleen.

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