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Future treatment options for human African trypanosomiasis.
1a Discovery Biology, Eskitis Institute for Drug Discovery, Griffith University, Don Young Road, Nathan, Brisbane, 4111, Australia.
Expert Review of Anti-Infective Therapy
|September 29, 2015
Summary
Human African trypanosomiasis (HAT) cases have decreased by over 90%. Continued research for new treatments is crucial to prevent resurgence and achieve HAT elimination goals.
Area of Science:
- Neglected tropical diseases
- Parasitology
- Drug discovery
Background:
- Human African trypanosomiasis (HAT), a significant public health concern, has seen a remarkable 90% reduction in reported cases over 17 years.
- Despite progress, achieving the goal of HAT elimination necessitates the development of novel therapeutic agents.
- Current drug discovery efforts have identified three compounds for clinical development against Trypanosoma brucei spp.
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