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Updated: Apr 2, 2026
04:41
Plaquing of Herpes Simplex Viruses
Published on: November 5, 2021
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[ESOPHAGITIS, CAUSED BY HERPES SIMPLEX VIRUS: CASE REPORT].
Summary
Herpes simplex virus (HSV) caused esophageal lesions in a 56-year-old patient with severe swallowing pain. Antiviral treatment with acyclovir rapidly resolved symptoms, highlighting HSV esophagitis as a treatable condition.
Area of Science:
- Gastroenterology
- Virology
- Infectious Diseases
Background:
- Herpes simplex virus (HSV) commonly causes oral and skin infections.
- Esophageal involvement by HSV (herpetic esophagitis) is less common, particularly in immunocompetent adults.
- Odynophagia and dysphagia are key symptoms, often necessitating differential diagnosis.
Observation:
- A 56-year-old patient presented with severe odynophagia and dysphagia.
- Initial treatment with proton pump inhibitors was ineffective.
- Endoscopic examination revealed extensive esophageal ulcerations.
Findings:
- Polymerase chain reaction (PCR) testing of esophageal biopsy specimens confirmed the presence of herpes simplex virus.
- Treatment with the antiviral medication acyclovir resulted in rapid and complete clinical recovery.
Implications:
- This case underscores the importance of considering herpetic esophagitis in the differential diagnosis of severe esophageal symptoms, even in non-immunocompromised individuals.
- Prompt diagnosis and antiviral therapy are crucial for effective management and symptom resolution.
- Further literature analysis supports the clinical significance and current relevance of recognizing HSV esophagitis.
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